Category: Life course

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L’échiquier

The game of chess has been subject of an ever increasing amount of literature. Not only historically the game, where two kings fight against each other, but the queens are the most powerful figures on the chessboard attracted a great deal of attention. We studied chess in books and watched live tournaments between the best players of the world. Most of this has successfully moved online and we have gotten used to losing against computers for almost all human beings some time ago. The internal federation of chess FIDE lists the top players male and female. The calendar of face to face events is still impressive. The federation operates somehow like a platform of players, as well as for players, to organize their lives as chess players. Anther kind of chess literature is the one that is constructed around the lives of chess players. Some characters get really absorbed into the mental or virtual world of the dialogue between 2 or more characters or players. The real world experience and the game on the board become intertwined or entangled. Losing or winning, to win or not to win, may unbalance whole personalities. Beyond the “Schachnovelle” von Stefan Zweig we have a new addition of fictional writing with autobiographical traits by Jean-Philippe Toussaint (2023) on our desks. « L’échiquier » is a story unfolding in 64 chapters just like the 8 x 8 spots on the chessboard. Of course, the story does not unfold in a linear fashion. It seems as if the players or opponents even change as the game unfolds. Maybe there are more than one game in action. Simultaneously as in some chess tournaments. Some games are blitz games taking just a few minutes, others go on beyond a lifetime. The experience of playing chess even against yourself has a psychological and sociological dimension. You can go round in circles for some or you are like “bowling alone” in the individualized society. About time to shed an additional light on the mystery of the chessboard. Self isolation with a chessboard was also a way of coping with the Covid pandemic. Some still suffer from long Covid and cures are not always easy to find.

L’échiquier, chessboard, Schachbrett
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Schubert Franz

Franz Schubert hatte ein kurzes Leben. Geboren in 1797 verstarb er bereits mit 31 Jahren. Seine Lieder werden nach wie vor viel gehört und aufgeführt. Mit 10 Jahren wurde er vom Hofkapellmeister Salieri in Wien bereits als Sängerknabe in die Hofkapelle aufgenommen, was gleichzeitig die Aufnahme ins Stadtkonvikt bedeutete. Seine Lieder wie „Der Lindenbaum“, „Die Forelle“ oder „Die Rose“ blieben lange Standards in den Musiksalons und Konzerthallen. Beeindruckend bleibt auch die Schaffenskraft des jungen Schuberts der in seinem „Liederjahr“ 150 Lieder komponierte. Seine Versuche eine Oper zu schreiben waren weniger erfolgreich. Das hat dann fast 200 Jahre gebraucht bis die Pariser Opéra Comique diesen Traum Schuberts erfüllt hat. Vielleicht hatte es etwas mit seinem Lehrmeister Salieri zu tun oder den hohen Ansprüchen der Wiener Klassik in der damaligen Zeit. Friedrich von Flotow hatte den Weg nach Paris gefunden und war sich der Bedeutung des ausdrucksstarken Librettos bewusst. Orchestrierung zur Verpackung der Lieder wird dabei bedeutsam. Flotow sollte das Oeuvre Schuberts bekannt gewesen sein. Erfolge mit eingängigen Melodien haben beide feiern können. Jeder auf seine Weise.

Schubert Sekundärliteratur
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Personal Health

Most people would agree, health is a personal issue. From the onset of life, we have package of genes that predetermine a number of factors of our personal health. Epigenetics has taught us there are many factors to take into account additionally. Environmental factors have huge impacts as well. Improvements in the availability of medical devices in the hands of individuals as well as AI systems on portable devices like smartphones facilitate the monitoring of personal health. Several indicators of early-onset of illness can be retrieved from such devices. Dunn et al. (2024) show that prior to the onset of symptoms of Covid-19 or influenza portable devices can indicate the presence of infections through indicators of resting body temperature, heart rate/min, heart rate variability/millisecond or respiratory rate/min. Combined with the indicators of air quality, indoors as well as outdoors, the presence of allergens a much more personalized data set emerges which can easily be part of an AI-assisted diagnosis. More abundant personal health data and analytical power allows remote and digital health applications to inform patients, medical doctors and the public at large. Digital health technologies are only at the beginning to unfold their potential. Prevention becomes more feasible using such devices, medical professionals should be allowed to focus on interpretation of data and treatment rather than simple data gathering. Thinking about digital health technologies points in the direction of dealing with climate and environmental hazards as sickening causes more forcefully. Personal medicine and personal health are, after all, still heavily dependent on health and safety at work, commuting practices and all sorts of pollution. Personal health, however, is a good starting point to raise awareness of the potentials of digital health technologies to better our lives.
(Image: AI MS-Copilot: 2 robots run in a city. They sweat. The air is full of smog. 2 other robots rest near pool. All look at their wrist watch showing heart beats)

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Error 444

The error message 444 is a not so rare encounter while surfing on the web. The error code 444 stands for the message that from the side of the server the connection is closed without any additional message. The occurrence leaves you without further indication of what exactly went wrong in building a connection to a web service or website. You just simply get shut out and that’s it. It may be tough on you if concerns your online banking or other access to vital services delivered through the internet.
In organization science and social science there are many new studies dealing with the finding, dealing, coping or handling errors. It has become much more acceptable to deal openly with errors, blunders or failures. From an individual as well as organizational perspective the cultures that deal openly with these events seem to have a certain advantage to overcome the consequences of errors at all or faster than others.
In some biographies failures are part of the lessons learned throughout life. It is deemed important to acknowledge failures or paths not taken for better or worse. Organizations just like individuals seem to learn more intensively from their failures or omissions than from everything seemingly running smoothly. Learning curves are faster also for “machine learning” if you have access to a huge data set which contains ample data on failures rather than encountering failures after release. Hence, the compilation of errors is an important part or early stage of a learning process. Failed today? Fail again tomorrow. You’ll be really strong the days after although it might hurt.

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Sepsis

Sepsis is a major cause of mortality. Therefore, early detection of sepsis is of high importance. Antibiotics constitute a powerful antidote. However, the application of antibiotics without need, i.e. for purely risk reduction in general, has side effects in antibiotics losing their effectiveness later on.
The paper published in The Lancet Digital Health by van der Weijden et al. (2024) reports on the effort to provide an open source access to a calculator of early onset of sepsis (Link). The Neonatal early-onset sepsis calculator developed by Kaiser Permanente builds on the use on the risk carried by mothers like time since membrane rupture, regional infection risks of mothers per 1000 population and the infants presentation at birth. It is important to point out the combination of risks put into the calculator. New systems of artificial intelligence might equally make predictions or recommendations about the application of antibiotics implicitly making use of such a calculator without disclosure.
From a sociological point of view it is interesting to scrutinize the indicators used in the calculation. The approximation of mothers carrying a sepsis risk relies on national, regional or better local indicators. This information is rarely accessible to the public. The choice of a hospital, speed of access to it in case of membrane rupture as well as staffing come into the calculation of an overall risk of sepsis.
It is great to follow the progress of digital health and the increased transparency of critical health decisions at the earliest stages of the life course. Inflammation as a precursor of sepsis should be taken serious at all stages of the life course. (Image calculation based on Kaiser Permanente digital tool Link)

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Processed food

We eat a lot of pre-processed food. Our busy work schedules allow us to take only short breaks for meals in order to get more work done while in office or at work in general. The intensification of work has reached the next level and we move from pre-processed food to ultra-processed foods (UPFs). In medical journals and nutrition recommendations the warnings to not eat too much ultra-processed foods are abundant. The signs of obesity in societies reach higher levels from year to year. Especially younger people seem to be at higher risks to consume a lot of ultra-processed foods. Freisling et al. highlight the “risk of multimorbidity of cancer and cardiometabolic diseases” due to UPFs. The discussion between scientists is a lot on which UPFs are most harmful (beyond animal origin or and artificially sweetened beverages) and/or whether it is the combination of UPFs that additionally increases the danger of UPFs. Preventing the “too much of each” is probably the safest recommendation. Being able to read the nutrition information on the labels is already a difficult task. Just making the information abundant and very small print discourages most efforts to compare across products. Learning about basic human needs like food has never been more difficult. Combined with “shrinkflation” we have a hard time to make informed choices of what to buy and eat. There are many hurdles to overcome for a healthy meal.

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AI and Behavior

We start to analyze the impact of AI on our behavior. It is an important question to be aware of not only how we interact with AI (Link), but also what effect the use of AI (disclosed or not) will have on our social behavior. Knowing that AI is used might change our willingness to cooperate or increase or decrease pro-social behavior. The use of AI in form of an algorithm to select job candidates might introduce a specific bias, but it can equally be constructed to favour certain criteria in the selection of candidates. The choice of criteria becomes more important in this process and the process of choosing those criteria.
Next comes the question whether the announcement includes as information that AI will be used in the selection process. This can be interpreted by some that a “more objective” procedure might be applied, whereas other persons interpret this signal as bad sign of an anonymous process and lack of compassion prevalent in the organization focused mostly on efficiency of procedures.  Fabian Dvorak, Regina Stumpf et al. (2024) demonstrate with experimental evidence from various forms of games (prisoner’s dilemma, binary trust game, ultimatum game) that a a whole range of outcomes is negatively affected (trust, cooperation, coordination and fairness). This has serious consequences for society. The social fabric might worsen if AI is widely applied. Even or particularly the undisclosed use of AI already shows up as a lack of trust in the majority of persons in these experiments.
In sum, we are likely to change our behavior if we suspect AI is involved the selection process or content creation. This should be a serious warning to all sorts of content producing media, science, public and private organizations. It feels a bit like with  microplastic or PFAS. At the beginning we did not take it seriously and then before long AI is likely to be everywhere without us knowing or aware of the use. (Image taken on Frankfurt book fair 2017-10!)

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Stroke

A stroke is a very serious medical incident. The NIH defines it in easy language as the the moment in which “blood flow to the brain is blocked or there is sudden bleeding in the brain“. Thanks to a European HORIZON project  forecasting models are produced to estimate the likely incidence until the year 2050 by age and gender within Europe. The good news is major regional imbalances of incidence and mortality have been reduced and will likely be reduced across Europe. The challenge remains the aging of societies which necessitates to address the issue of strokes in each single region of the European Union. We know that the shorter the time to treat a stroke immediately after its occurrence, the better the survival chances and the better the prognosis for (partial) recovery.
In the US the widespread use of blood thinners which tripled over 30 years has not lead to the reduction of intracerebral hemorrhage (Link to studies). High blood pressure and arhythmic heart beat are major causes of this often disabling medical event. The study by Wafa et al. (2024) uses age-pyramids to demonstrate the effect that as European societies are aging the incidence of intracerebral haemorrhage occurs with increasing age and even more so for women than men of 80 years and older.
Prevention of high blood pressure through walking or careful endurance exercise seems even more indicated for an aging society.
Image below from Wafa et al. (2024), The Lancet Regional Health, Europe.

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Force of dependency

Drugs have their particular strength in creating dependency. This is well known for tobacco or alcohol. Helping people to overcome the forces of dependency has its merits. At the same time it is big business. Vaping instead of smoking might be a way out one dependence but into another one. In the end it is an empirical question how many persons can escape the force of dependency of both types. Important to test the probability to get rid of the dependency altogether. With respect to hard, life-threatening drugs like Nitazene the death toll keeps rising in the UK. In the latter case changing the dependency is already a success. The sustainable deflection from drug dependency has to address underlying issues and health hazards. It is a rather individual issue. Society wide evaluation studies need to inform the debate also about placebo effects. The force of dependency might not only be physiological but psychological or linked to the social environment. All these potential effects have to be carefully sorted out before simple pseudo-solutions are implemented. Even the price and availability of drugs is part of the overall equation to solve the force of dependency.

Arthur Sapeck 1887 Illustration, BNF Pastiche 2023-4
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Forced Labor 2024

Thanks to the ILO we have recent data on forced labor across the globe. At the time when the EU struggles to tighten the rules on decent supply chains, it is important to draw attention to the already reversed trend that worldwide forced labor is on the rise again. According to latest report by the ILO 27.6 million women, men and children were in forced labor at any day of the year 2021. This is even about 10% more than 5 years before in 2016. The fact sheet from ILO highlights the region that are practicing it the most but mentions at the same time that no region in the world has completely wiped out this criminal activity. Despite the SDGs containing a goal to eradicate forced labor by 2025 for children there is little hope that this will be reached. Controlling supply chains of the rich countries could be an important factor in identifying the states or companies which built their production model on forced labor. The fight against this practice is an enduring challenge. We cannot allow to shun away from the thorny issue. The price for labor is only one argument in the reasons for the persistence of forced labor, migration is also a force at work. This asks for specific solutions to country-specific or sector-specific problems. It is a global responsibility but needs partnerships across continents to reach better outcomes in the interests of humanity. Some countries like Germany have a historical debt to invest more than others.

ILO recommendations 2024-1