In the middle of May 2024 we tend to believe the Covid-19 pandemic is over. However, towards the beginning of the year 2024 in the U.S. we observed at the peak about 2500 deaths per week. 
In Germany deaths/week amounted to 250. Compared to the overall population size killing is more pervasive in the U.S. than in Germany. The map of the specialized agency “Centers for Disease Control and Prevention” (CDC) in the U.S. shows the coastal regions to be more affected than the center. Population density seems to be still a driver of the spread of infections, illness and deaths. The timeline of deaths due to Covid-19 infections for Germany follows a broadly similar pattern, albeit on a lower level even if roughly accounting for population size (RKI-data). As we tend to forget what the pandemic caused as social and economic disaster in societies, we have to stay alert as the major prevention of Covid-19. Learn to live with the virus around us. This means to keep up our preventive levels of hygiene as well as monitoring of trends.
Many thanks to all those who do the sometimes boring number crunching for us. This includes the medical doctors who bother to do the timely reporting of new infectious diseases on a regular basis.
Killing me softly
The problem with pollution is, it is killing you softly from inside. It is almost impossible to escape air pollution as it is pervasive in cities, but also in the countryside where you do not expect it that much. This is the result of the study by Kuzma et al. (2024) published in “The Lancet Regional Health Europe”. Based on a data set of 8 million persons from Eastern Poland the effects of air pollution on myocardial infarction incidence was analysed. The use of the “European Union’s Earth Observation Programme” contributed data on air pollutants like PMs, BaP (benzo(a)pyrene), SO2 and NO2 concentrations. The multi-level data of 5 voivodeships, 101 counties, and 709 communities in Poland allows to differentiate the effects of damage to the heart tissue on cardiovascular disease. The other well-known factors are arterial hypertension, diabetes, obesity, chronic kidney disease, hyperlipidaemia, and smoking as most of us know already. The effects of BaP (benzo(a)pyrene) is shown for rural areas despite the lower observed traffic density in these areas. The killing occurs softly from within our bodies by just breathing in and out, and in and out continuously. The disease burden in these regions is observed with “recorded 63,154 hospitalizations and 5921 in-hospital deaths (9.4%) due to STEMI; and 76,543 hospitalizations and 4079 (5%) in-hospital deaths due to NSTEMI”. In short, the need to reduce air pollution further is an urgent demand that saves lives eventually.
(Image from public domain wikipedia or “do-it-yourself” here).
Attune Spheres
In Berlin it is easy to walk through the history of art to up-to-date contemporary art installations. Just walk from the Alte to the Neue and then to the Contemporary Nationalgalerie. With the installation and performance in the monumental Hamburger Bahnhof the artist Alexandra Pirici succeeds in an extraordinary way the combined impression of several art formats. I felt particularly attracted by the sound and resonance that the dancers achieved in the huge historical hall of the former train station. Embedded in a choreography that spans the whole hallway and the top of a sand dune, the ideas of „Attune“ bring in demonstrations of scientific experiments as well. We are reflecting on how structures, biological, physical or geologic processes coexist. It is another example of the intersection of biological, psychological and social phenomena. The links between science and art are more direct than what most people tend to believe. This encompassing experience catches all our senses and our mind. It is very likely that this intense experience in the museum space, which attunes our sensory perception of the artwork, sticks with us for longer than many other pieces of art. The 21st century will reveal an even more powerful language of art as it incorporates even more formats to grab our attention and imagination. The research of how patterns are formed is an important question for social scientists as well. All approaches to the subject are welcome and each one reveals our knowledge gaps despite remarkable progress. (Image: Hamburger Bahnhof, Berlin 2024-5-11, Alexandra Pirici) 
Silent Pandemic
There is a pandemic that is silently spreading across countries and continents. It only indirectly related to the Covid-19 pandemic. The medical journal “The Lancet Respiratory Health” (2024) has an editorial about the inequities of asthma as they develop over the life course. The development of asthma has pre-natal, genetic, environmental, life-style and socio-economic co-determinants. The study of respiratory disease, therefore, is a multi-factorial issue, which needs to disentangle the specific influences. Smoking as well as obesity have an impact on asthma, instantaneously or with delayed time effects of sometimes many years. Hence, it is important to take the whole life course into account, if we want to address the rising disease burden of asthma. Air pollution and heating-up of the planet are important drivers of the silent asthma pandemic across the globe. The social distribution of people working in “asthma- prone” work environments and/or living in highly polluted urban, suburban or rural areas near high frequency traffic is another latent factor causing huge costs to persons and society as a whole. Health inequity is growing over the life course. This is not easy to tackle as policy target as the onset of the disease has no single trigger, but rather a combination of influences that contribute in varying amounts to the evolution of respiratory diseases. (Image air pollution https://aqicn.org/map/germany/de/)
AI Racing
AI has entered the racing of cars after we have been racing horses, dogs and camels for many decades. The fact behind all these races is the huge market for gambling. Anything you can bet on will do for juicy profits in that industry. The recent “Abu Dhabi Autonomous Racing League” is the latest addition to the racing craze. Moving online with 600000 spectators at its peak on video and gaming platforms the investment seems promising. The only problem, AI is not yet ready to really compete with the world of real drivers. The progress, however, is astonishing. Just one lap of 2 minutes on the circuit yields 15 Terrabyte of data from 50 sensors. These are closed circuits so no person can enter or animal can get in their way. The challenge to integrate more data and faster processing as well as algorithms for fast decision making is steep. Great learning opportunities for advances in robotics. The hype has not been able to live up to the expectations as no real racing took place yet. We have replaced the gladiators of the Roman empire with Formula 1 drivers. It is only fair to retire those drivers soon and let AI race cars against each other. It feels like a computer game on screen and it is as we shall most likely watch these races on a screen as well. Hence, what is the point. Watching youth on TWITCH play racing games will probably not change the viewing behavior of the masses. The programmers have nevertheless great learning opportunities and will find their way rapidly into the job market. The other challenges of ASPIRE seem more important for humanity like human rescue and food for the growing world population. In the meantime let the boys play around with cars and learn about potentials as well as failures of AI-programmers and dealing with both.
Puccini Media
In honor of Giacomo Puccini the Media enterprise Bertelsmann features one of its treasures. In cooperation with the “Archivio Storico Ricordi” of Milano, Italy, 100 years of Puccini’s oeuvre is celebrated with this exhibition. Fans of Puccini’s operas will have to visit the archives but the interest of this small exhibition lies in the impressive success story of Puccini and his publisher (part of Bertelsmann). Continuous innovation and adaptation to new media, like disks, accompanied an extraordinary marketing campaign throughout the 100 years. Even today there are cycling tours around Puccini’s hometown for the modern eco friendly tourists. We learn a lot about how the media industry functioned in the 20th century. It was absolutely vital to fighting for the rights of authors, composers and rights to receive royalties for performances as well as for the publishing on media. The exhibition in “Unter den Linden 1” is just next door to the Staatsoper which also gave honor to Puccini’s “Madame Butterfly” in 2024. His uncompleted Opera Turandot closes the exhibition with his rough sketches of the final scene. Merchandising is not an invention of the 21st century, but almost a century old tradition. This exhibition is a great testimony for this. It remains an important effort to allow authors and composers to gain a comfortable living during their lifetime. The gains for humanity as a whole are enormous.
Infinite Landscapes
The “Alte Nationalgalerie” celebrates the 250th birthday of Caspar David Friedrich in Berlin. With a considerable effort to unite in one exhibition many paintings and drawings that stem from other collections of public and private origins. This particularly remarkable as a section of the exhibition is devoted to paintings that were intended originally to be seen next to each other (compare catalogue p. 233). Comparing 2 images from the same painter evolve into a narrative. This raises curiosity as in some instances the 2 paintings do not treat the same subject. Your very own interpretations and associations will make for an individual journey through the sheer endless spaces. The exhibition allows to grasp some of the many questions posed by the period of enlightenment not only in Germany. After “God is dead” what will happen? How is mankind defined? What is its relationship to nature? Are we just left alone or what comes after individualism? Even for painters, much like scientists, it is just as important to pose the right questions. Leaving the exhibition with more questions than answers will put you in the “Berlin state of mind” of 200 years ago. Greiswald, Dresden, Rügen and Copenhagen as well as nearby mountains were influential locations and landscapes for Caspar David Friedrich. Berlin 1906 „Jahrhundert Ausstellung“ made him famous again, despite decades of being forgotten. Yet another question to ponder and wonder about. An additional merit of the exhibition is the section on painting techniques and the use of his sketches and drawings for the preparation of the oil paintings. The final riddle to be solved is the price differential between the German and English version of the catalog in the bookshop next to the usual merchandising props.
Weight Stigma
The fashion industry has for a long time produced images of mostly women and men that did not correspond to the normal weight distribution of people. Skinny models were present across all media. The so-called social media of today amplify this trend further. The “Barbie hype” has reinforced the idea of low weight as a socially desirable norm. In scientific research the term coined for this phenomenon is “internalized weight stigma” (IWS). A study shows (Highes et al. 2024) it affects more women than men and more people who are described as socioeconomically disadvantaged adults. Pressure to lose weight originates from multiple sources and social media platforms have given rise to bullying. A major outcome of IWS is eating disorders as eating is often wrongly associated to be the only cause of higher weight. It is not. Many other factors contribute to the actual weight of a person. Even the overuse of the body mass index (BMI) as short hand version to define overweight or obesity is misleading for persons with strong muscles. Just fixing on one parameter of body shape or weight tends to reinforce weight stigma. “Keep walking” and a regular healthy diet, this avoids to internalize a weight stigma. Exercise is fun, the more you do it in a group, the easier it is to get going regularly. We ought to keep trying and eventually it will become a routine.
Screening Paradoxon
In the field of public health the screening paradoxon is a well-known feature of large scale programs to check for and contain the large increases in cancer among populations. A recent medical study underscores the necessity to curtail the screening paradox in Europe. The screening paradoxon is defined as “the underuse of screening by those with unhealthy lifestyles and high risks”. The opposite cases, “the overuse of screening by those with healthy lifestyles and low risks” only cause a problem for the costs of the health system as those unlikely of attaining a form of cancer make extensive use of screening. In terms of social inequality we have to be concerned about both ends of these distributions. The publicly available screening programs are skewed towards the higher educated with risk awareness as well as healthy life styles. More of them participate in screening. The other distribution of actual risks and detection of cancer is skewed towards the other end of the risk distribution. The 2 probability distributions overlap to an extent that is most likely co-determined by cultural factors like general attitudes towards prevention.
With the increase in cancer rates generally and due to demographic aging of societies, we shall need to target our resources devoted to health more precisely rather than spending too much on screening of people with very low risks. Increasing the duration between screenings might not impede detection rates of those with healthy lifestyles, but could allow to devote more resources to those people who are hard to reach by screening programs so far. Evaluations of such programs are necessary to judge the need for more targeted programs.(Image own representation inspired by Ola et al. 2024)
Barbie Chemical
Chemistry is sometimes perceived to be uninteresting, but only until you realize it might be beneficial to know more about some underlying chemical processes. The Royal Society of Chemistry has finally found a topic in chemistry to give chemistry a popular push. The Barbie hype is far from over as we all learned in the recent past. Now conservationists have found a topic with chemical processes involved to demonstrate the usefulness of chemistry knowledge for the conservation of your treasures or collections of plastic dolls or puppets in general. Most plastics PVC was not intended to last, but the deteriorated forms have a long lasting effect in form of PVAS or microplastics. So aging research has reached popular concerns like the aging of Barbie, who is believed to be “forever young”.
