The empirical evidence on life stress is relatively clear cut. Based on the animal model, life stress causes multiple metabolic disorders among them “insulin resistance, glucose and lipid homeostasis, as well as ageing processes such as cellular senescence and telomere length shortening” (Kivimäki et al. 2023). Besides sleeping we spend most of our life in work-related contexts. Stressful commuting to work and stress at work create a rather unhealthy lifestyle. More stressful working lifes have very likely contributed to currently increased risks of obesity around the globe. Unhealthy nutrition adds to risks just as too little exercise or walking. Time to act for the benefit of all of us. It is not correct to put the blame on individuals, if we know that work and life styles jointly contribute. Urban planning can do a lot to contribute to insulin resistance of inhabitants through more walking or cycling paths for all not only in the wealthier suburbs. The more stressed winner of the daily race might come last in the longer run.