Illness duration

The focus in medical analyses is primarily put on the diagnosis of illness. This is the best strategy, if the onset of an illness has a precise beginning and ending. In all processes, where either the beginning and/or the ending is less well-defined as precise point in time, the progression, as phase in or phase out of illness, is also of substantive interest. A duration analysis can inform about the potential presence of a co-morbidity in case, for example, an infection continues beyond the normally expected duration.
Financial pressures in the medical systems makes it necessary to release patients in a timely fashion. Therefore, has become more important to monitor patients even after release from hospital. Digital devices can support such a monitoring.
The study by Josi Levi and co-authors (2026) shows that smartphones or just the monitoring of the number of steps of patient offers a rather reliable indicator on the health status towards the end. The information that a patient has recovered to the normal level of activities as before the onset of the illness works quite well as indicator of recovery. A more precise measure of the duration of an illness is important for patients, care persons, the health system overall. The duration is one of the cost-intensive factors of any illness and it is surprising how little we know about the issue of time and duration in many health processes.

Metabolic harm

At the beginning of the 21st century the lack of physical activity for large parts of society has become a major risk of and cause of metabolic harm. We have become used to a sedentary lifestyle and the digital access to distractions and information have encouraged further immobility. Alex Broom et al. (2025) stress the importance to include social and governmental interventions into the many existing medical, pharmacological and technological interventions. The authors advocate a rather holistic approach to really make a difference. The obesity trends cause metabolic harm of an  unprecedented size. We have to rethink mobility patterns and other behavioral changes into our daily routines to bring back more stimulation to our metabolic system.

Alzheimer Research

Alzheimer disease has reached unprecedented levels in line with population aging. The study by Martino-Adami et al. 2024 has raised the hope that more people can receive an early diagnosis of Alzheimer and potentially start treatments. The study used plasma biomarkers rather than much more expensive and rare MRI scans for diagnosis. The rather exceptional results allow even to test for severity of Alzheimer according to established evaluation measures. Additionally, the probability of an Alzheimer trajectory on a time scale is feasible. The authors suggest that the data and statistical methods applied allow to identify Alzheimer before the outbreak of impairments. The data sample stems from “patients of advanced age visiting primary care”. This remains a limitation for generalizations, but the hope that other studies test the same approach with samples from younger populations will spur additional investments into such research. The list of institutions and foundations that contributed to make this study possible is really long. Thanks go to all involved, researchers, donors as well as the reviewers and editors of the journal. (Image Paris Metro Help Column 2024)