The annual mortality statistics and special reports on suicidal tendencies are a tough reading. OECD Statistics give a at least an approximate, comparative perspective. Reporting routines and medical confirmation of a suicide or suicidal behavior still vary quite a bit between countries. Nevertheless, the usually reported incidents per 100.000 persons remain rather abstract.
Absolute numbers speak a clear language. For example in Germany there were about 10.300 recorded suicides in 2023, France had to mourn about 9200 in 2022. To put the size of the problem in perspective it is helpful to know that in Germany all other not aging related causes of death like traffic accidents, drugs or murder make up for around 7.000 deaths per year. The targeting of resources and prevention efforts on these vulnerable people seems inevitable. However, we see only limited additional efforts to curb the problem.
A more detailed analysis of the frequencies reveals the gender and age differences. More men commit suicides and older (very old) people have higher risks. The oldest age group of men is most at risk.
Since the Covid-19 pandemic young women show rising trends in many countries again of suicidal attempts and self-inflicted wounds. Despite a continuing effort of research (Links) there is no single cause to explain the occurrences.
As a working hypothesis, which awaits empirical tests, I would look into societal factors that stigmatize persons who are made to believe or feel like they are beyond the normal spectrum of society. The lack of acceptance of diversity concerning gender, age, ethnicity, body shapes or mental states like anxiety. Poverty might cause immense distress and suffering. Large shifts in wealth in both directions cause additional risks.
It seems as if our minds and society are constantly in a kind of „regression towards the mean“ posing challenges to those furthest away from the average or perceived norms. Percentile ranks or percentile scores are commonly used to express a person’s position in a frequency distribution. For example you are better/lower than 90% of persons of your age group. Such statements might cause further distress for persons. However, summarising across several (psychological) measurements, they may yield encouraging indications as well. Actual and perceived positions in such percentile ranks add another “social risk” as perceived positions may govern behavior.
Blue Sky
In the period of romanticism the associations with a blue sky were very different from today. Getting out into the sun was a kind of privilege for the “leisure class”, of people who could afford to enjoy time outside for boating, walking or other pleasures. In our technology-driven 21st century the associations with Blue Sky are more like a technically enhanced view through for example “Windows” at the news and opinion platform or “Bluesky”.
Several scientific websites that report data on blue skies and air quality more generally across the world report indicators like ozone values O3, sun intensity, micro particles 2.5µm and 10µm, Nitrogen Dioxid NO2 to name the mostly quoted indicators. Hence, just enjoying the blue sky outside isn’t the same as it was before. People working outside in the sun or at times of a blue sky but with high air pollution levels are incurring severe medium-term health risks. The Ozon layers at very high altitudes protect our skin and eyes against high UV-radiation, but O3 on the ground is tough for eyes and lungs.
Technology has come with many blessings, but the negative effects on a global scale become also more evident. Getting used to a particular lifestyle, which produces lots of emissions of aggressive fine particles will make it more difficult to just simply enjoy a blue sky.
In consideration of all these background data with regional variations, we surely need an AI-system which we can ask for advice, whether we should go outside and enjoy the blue sky with or without respiratory mask.
Romanticism has led us all the way to Californication and dangerous enshittification of the air that surrounds us. Youth and the next generations will have very different associations with Blue Sky than we have the chance to, at least, have had.
Mindmap Me
Tools like artificial intelligence allow all sorts of transformations and depictions. The photo editing tools are widespread and particularly popular among the young users. My own transformative exercises, latest with www.bairbe.me, have yielded interesting insights, well worth an intergenerational playmate. For the guys there is the www.yobrick.com version for brick gamers.
The App “Canvas” allowed me to delve deeper into my own mind by giving instructions of how to create an image of the structure of the blog entries on this webpage. Of course, it is not (yet) a real AI-generated content map, but it is only a matter of time until such tools will exist. After all, this would be just an arranged and rearranged list of contents using the hyperlink structure of the texts as well.
For the time being, I derive my own structure of the blog entries by topics, categories and tags including the hyperlinks or internal referrals. Interlinkages are mostly stated explicitly. However, there are many implicit links, which are obvious to some, but not others. AI-systems could use occurrences of words, synonyms and antonyms . Colors in addition to bubble sizes and (in)direct lines may complement such mindmaps. This can help to reveal another, additional layer to connections between categories or tags. The Ai-generated image shown below was created with the APP Canvas as a first approximation and AI-augmented test version in form of abstract images).
Next steps on the way to understand human intelligence and, maybe, augment it with a next generation AI-system would use a colored-3D version of such a mindmap and use the chronological evolution of the blog posts in a kind of evolutionary animation. This should allow us to go beyond the usual psychological classification of fluid and crystallized intelligence. We might come to grips what it means to be “in a Paris state of mind” or when hallucinations become overwhelming.

Existence as Eggsistence
Artists have their own ways of hallucinating. They don’t need an AI to generate ideas beyond the normal, even allowing for 2 standard deviations off the usual. As a result of the thorny question about your existence, Ram Katzir came up with the impressive statement about his „eggsistence“ being subjected to a squeezed experience. Ever increasing shares of the labor force would subscribe to this statement about the modern workplace. Each turn of the screw risks to crack up the egg‘s shell. Rather focus on the egg, try to get a grip on the screw. There are thousands if not millions who crack up under the excessive pressure of economic and political circumstances. The new platforms of food, grocery and parcel delivery at home have become the latest example of AI-assisted and algorithmicly managed screws. What is driving your eggsistence. It is about time to ask fundamental questions again. (Image: Eggsistence, by Ram Katzir 2021 in Brussels, Galilas Collection Belgium)
Holocaust Remembrance
The 80th anniversary of the liberation of the concentration camp Auschwitz-Birkenau marks a very special kind of remembrance. As the number of survivors of Nazi-terror and genocide is shrinking the testimony of survivors is becoming more rare and more precious. According to the “Jerusalem Post” on 2025-1-28 (p. 9) the number of survivors that came back to the site of horrific crime has shrunk from 300 ten years ago to 50 in 2025. The strength and courage to continue to testify amidst having reached 90+ or even 100+ years of age is a “living memorial” of its own kind.
Many television stations across Europe have followed the example set by this special Holocaust remembrance day and focused equally on recorded testimonies or additional live interviews of survivors. Please keep repeating these testimonies to confront people with the outcome of Nazi-terror in Europe. The choice this year was a courageous one. Instead of speeches of sorrow and lip service to fight antisemitism by acting politicians, the focus on the testimony of survivors in public, on TV and to large audiences will encourage others to continue to give testimonial of these horrors.
(Image: extract of Pressreader newspaper titles 2025-1-27)

Synthetic opioids
Across the globe there are many tough lessons to be learned about synthetic opioids. These psychoactive substances fall under special legislation and can only be used with medical prescriptions. The strength of these substances is usually compared to heroin and the risk of addiction to these substances is very high.
A recent paper in International Review of the Armed Forces Medical Services (2024) has highlighted also “the abuse of the synthetic opioid U-47700” at times of military conflict. The power of these drugs to suppress the feeling of pain is helpful for medical operations. The abuse, however, may consist in the use of the drug to “keep fighting whilst pain is suppressed”. Such use of synthetic opioids increases the risk for addition and the fatal consequences of overdoses. The reporting of such occurrences in a specialized medical journal is an important warning against the conscious and willingness to abuse the drugs for war purposes.
The finding reminds us of the abuse that was already widely spread during the Nazi led 2nd World War (“Der totale Rausch“). The addictive potential was experiences even after the war time in terms of active combat was over. The costs to society of such abuse as well as use of supply chains of provision of opioids during peace times remain a problem for many years after the war. After a war, the war on drug abuse continues. Fighting addiction is a lengthy and painful process.
Defence Spending
As in research there are many dual use products, which can be part of defence spending. Robotics in production or rockets to launch satellites for telecommunication are such examples. Much less known to the public is the amount of military spending that goes into medical developments that benefit both the military as well as the civil population. Countries build a whole ecosystem round the provision of medical services for defence purposes , which consists not only of a sufficient number of qualified persons, but also companies that provide specialised products. Most of them have civil applications as well after minor adaptations.
Oxygen provision was a prominent example of a product that has civil and military uses in treatment of respiratory infections or contaminations. A mobile transportable operation table is another element of daily rescue services as well as potential use in situations of conflict, just like anesthesia machines. An increase in spending on such infrastructure and the necessary long-term training of persons operating and maintaining these medical applications take time and considerable financial resources.
The current debate in Europe and NATO neglects the considerable time delays in production and provision of the equipment. Research on “Skill Needs in OECD countries” has shown the substantial delays between sudden skill needs and the time to train high-skilled persons.
The International Review of the Armed forces Medical Services is a journal dedicated to publish up-to-date information on needs of medical products and persons trained to use them in special emergencies. The need to safe lives in extreme and dangerous conditions needs preparation of thousands of specialists. Of course we hope that such an incidence will not happen. The persons and material have an obvious potential to serve the civilian population in more peaceful times as well. The unfortunate “hog cycle” in skill provision is not a problem for dual use products or services.
(Image: edited extract of a mobile operation table)
Obesity Revised
The scientific paper on a revised definition of obesity was produced by the special Commission on Obesity. It appeared in The Lancet Diabetes & Endocrinology in 2025-1. The previously common practice by medical doctors was to classify person in the obesity category based mainly on the simple calculation of the body mass index (BMI = weight/height²). A BMI > 30 put persons into the obese category and stigma.
Since the Covid-19 society-wide testing experience, we are all familiar what it means if you get misclassified and have to live with the consequences (exclusion from work or events etc.). The simplifying and summarizing BMI calculation and classification has also produced many wrong classifications. For example, persons with a lot of muscles (just watch this at any fitness studio) will have a high weight relative to their body height², but they are likely to be more healthy than many other light weight, but seriously stressed persons.
In empirical test theory such cases are the so-called false positive cases, i.e. classified as obese, but not a medical problem at all. Medical doctors and health insurances should not finance special treatments for these persons, which foregoes treatment of other more needy persons.
With new expensive drugs on the market to treat obesity it is even more important to test with more precision the normal, pre-clinical and clinical status of obesity. Fatty tissue or muscles, that is the relevant question. Fatty tissue in muscles is the next level testing issue.
Enshittification
Don’t laugh. This is a very serious scientific term to describe the way social media function in the 21st century. The scientific reference goes back to 2025 and article in “Science” by Kai Kupferschmidt. Twitter, now eXit, like most other social media platforms uses algorithms that select posts for you from the millions of posts that are likely to induce a reaction from you, which prolongs your time on the platform. Additionally, eXit Twitter applies an algorithm that prioritizes accounts with already a huge followership, which makes these accounts even bigger. The result is an increasing inequality in attention to info, facts, fake news, but also revenue for the platform owners through more advertisements. As hate speech and fake news are commonly perceived as shit, many social media are happy to spread more shitty things on their platforms as this generates more money for the platform as well. In short, enshittification happens sooner or later to most platforms and we all suffer from this. As user of these platforms, it is hard to escape from this process, as most platforms tend to “convert” to enshittification at some later point in their life cycle, unlike babies who manage to quit this phase after a few months. A move to Bluesky might be indicated, but there is no guarantee that the same process will just happen again. Mastodon is another small twitter-like platform that like Bluesky offers a more open approach to its governing algorithms and a more controlled access in the registration process.
To avoid enshittification, we have to be ready to move away from one platform to another one, just like changing bank accounts or club memberships. Make sure to take most of your friends with you and there are already tools for this online as well. Enjoy the safe online life again on another platform or consume more of the traditional media like newspapers, radio or tv with proven quality. (Image: extract from Jan Steen, 1625-1679, The Rhetoricians – “In liefde vrij”, MRBAB)
Science and Fiction
We associate with science and fiction the extrapolation of scientific trends into some futuristic settings. The most striking examples of science fiction in novels or video use some scientific findings (dinosaurs, genetic engineering) and project this knowledge into another fictional setting. The usual personal relationships follow rather predictable plots of romance, deception, violence or war.
The novel “Wellness” (Hill 2024) is also a kind of science fiction as it is based on social science evidence and builds its fictional plot firmly embedded into the social and psychological research. The attachment of references (and defending the print of those in translation) underlines the commitment to write a new type of “social science fiction”.
In this innovative style the scientific basis of psychology and sociology is then extrapolated into a fictional arrangement. Research on subjective well-being with the U-shaped form over the life course and the extrapolation of the placebo effect, which is instrumentalized for a business, derive from key topics in the social sciences. In fact, the novel and the background scientific literature in the bibliography could well figure in a social science course at university entry level. These readings constitute a 360-degree-view on personal development and social structures. Of course, social sciences move on and add new evidence on an almost daily basis, but the selection and arrangement of the characters create an innovative social science fiction, without some unrealistic technological extrapolation.
It strangely feels like we are already part of this social science fiction (compare “Klara and the sun” by Ishiguro) as politicians advocate and campaign with placebo topics in elections and project us into some more happy past or future.
The social science fiction of Nathan Hill resembles for me the great utopian novel by George Orwell “1984” published in 1948. A title “2032” instead of “Wellness” could have worked quite well, as the first edition of Nathan Hill’s social science fiction was published already in 2023. (Image: Extract of: Lo Spagnolo, 1665-1747, Hecuba makes Polymnestor blind, MRBAB).
Not learning
For decades our attention has been focused on how learning works. However, at the beginning of 2025 it might be more important to shift our focus of learning research on “not learning”. Recent research on learning includes the study of “social learning” of mice (Winiarski et al. 2025) and the related brain mechanisms that are involved in social learning like the prelimbic cortex.
For our human societies we also rely to a great deal on social learning. In mice, however, the disruption of the prelimbic cortex causes mice to no longer seek “social information related to rewards” from other mice. In Eco-HAB cages these mice follow their scent capabilities to “sort” their information seeking from for example higher “social status animals”. This tested reward seeking behavior allows clues to how learning works. The intervention to disrupt the synaptic plasticity in a later phase of the experiment reveals less social learning from the network social information and fewer contributions to the social network.
Only intact neural plasticity in the prelimbic cortex ensures the maintaining of the social structure. Of course it is highly questionable, whether these results based on animal experiments tell us anything about social structure and social learning in other mammals, but there might be reasons to search for explanations of “no social learning” in humans as well.
Wellness Sickness
There appears to be some kind of a relationship between the 2 conepts of wellness and sickness. Some would argue that the more sick you are, the more you seek wellness. Sickness seems to be the precursor of wellness for many people. Wellbeing or happiness are even higher order concepts which are only indirectly related to wellness. In an almost 600 pages science and fiction novel, Nathan Hill (Link) constructs his plot based on the psychological research on the placebo effect. With a sufficient aura around a pseudo-medication administered in a wellness clinic, the clients or some figure near the 50% random positive effects are treated with at least no negative side effects. On page 152 we find the more explicit description of how to induce a placebo effect in participants. Context, expectations, faith, symbols, metaphors and story are all ingredients for a placebo effect to work. Sometmes without knowing we receive a treatment in our childhood or throughout the life course that we work on using placebo effects to overcome them. The novel by Hill (2024) is a well researched psychological as well as sociological fiction including a bibliography, which reminds us „If you cling too hard to what you want to see, you miss what’s really there.“ (p. 496).
Investment Disinvestment
Asume we live in a world of fixed amounts of investments. The option to invest in a new project or product will automatically reduce the amount of investment in another product. The investment decision, therefore, is subject to opportunity costs. A recent study by Naci et al. (2025) applies this rationale to the investment in new drugs compared to financing other traditional treatments. The results for the U.K between 2000 and 2020 revealed that the „quality-adjusted life-years (QALYs)“ is not in favor of the investment in new drugs. The relatively small numbers of beneficiaries of the new drugs is compared to the many other persons who could have benefited from the less costly previous treatment. Investment in one new drug causes disinvestment in other ones. The overall balance for the UK turned out to be negative. Particularly the disinvestment in prevention of diseases appears to have very detrimental effects in view of the results based on this study. Preventative measures are relatively cheap compared to the estimated 20.000 pounds for one additional quality adjusted year of life for a new drug. The message is: choose your health investments wisely to avoid ever rising health costs and health insurance. (Image: rest room Belgium)
No tobacco Sweden
Sweden is the forerunner as country with the lowest number of smokers across Europe and probably even the world with only 5% of the population 16 years and older. The success of these public health policies is due to banning smoking not only form pubs and restaurants, but also outside in the surroundings of public spaces like schools, playgrounds, train stations and sports facilities. These policies work quite well and the effects of discouraging smoking in public is reduced to a minimum rather than the normal encounter.
Health of the other persons and children passing through these areas is not the only goal. A new estimate of lost days or years due to smoking based on a study from England shows that “each cigarette smoked reduces the smoker’s life by about 20 minutes (17 for men, 22 for women, LINK to study). Of course, there is a huge variance and other work and life conditions that play an important role as well, but the broad average estimate is a nice way of talking about statistics. The basis of the estimate is for those who stop smoking and not those reducing their tobacco intake by some percentage or replacement product.
In the Belgian football stadium (image below 2024) in Brussels the No tobacco sign is well placed to make parents of children and youth understand the challenge ahead. Good resolutions are assisted by gentle regular reminders as well.
Air Concept
Well yes, this is the latest fart in design and architecture. The Berlin International University of Applied Sciences composed an exhibition on “Air Architectures” which takes air seriously. The international group of 7th semester students took Air Architecture seriously and developed their ideas in the context of a curated exhibition. Nice semester project.
Air is a fundamental precondition for humans to (co-)exist. The biology of air (breathing) or the chemistry of air (fine particle matter) have been studied extensively. The physics of air flows in cities receive more attention as well in architecture. Interior design has yet a lot to contribute in the age of heat pumps and air conditioning.
Let’s think architecture from the perspective of air and air flow. Depending on our cultural background we might have very different associations with air. Indian or Chinese practices like yoga or Tai Chi teach us to take air more seriously than Western practices. Most architecture in cold countries of the northern hemisphere aim to keep air to the outside of buildings. Yet, the percentage of humidity of air is a serious concern of architecture as well. Air flow and quality then becomes a key issue of construction and architecture, somehow through the back door.
Maybe in approaching architecture we might think first of what is or has been the architect’s concept of air or aerodynamics. 100 years after the death of Gustave Eiffel and the Olympic Games in Paris, we still gain from thinking about air (not only air pollution) and its dynamics. Looking forward to the next generation of air architects.
(Image: Exhibition, Air architectures, at Berlin International, University of Applied Sciences 2024-12)
Kids Space
Political claims to reserve more space for kids in cities have a tough time. Kindergardens or child care in general are scarce and the lobby for kids is often limited in time and extent, since it is the parents that usually are the ones to advocate while their children are small. Jointly parents and children of young age experience the tough atmosphere to find, preserve or extend the space for kids.
The Gropius Bau in Berlin has opened up an exhibition space reserved to children 3+ as part of an art project “BauBau” designed by Kertin Brätsch 2024. A colorful room and installations as “loose parts” are the starting point to delve into a real/fantastic world were kids reign. There are a few so-called “playworkers”, who accompany the endeavours, if need be. At the end of the day the room was still in pretty good shape I would say assuming that “children set the tone and decide what happens in this place”. Safe and supportive environments for children are scarce and parents are always challenges in their attention to watch out for risks of all sorts in public city spaces.
Even if the “play space” is free of charge, it takes parents or kindergarden managers to reserve the space.
An early experience of a museum from the inside is likely to have lasting effects on children and the parents. They might have fond memories of a museum as an exciting space also for them. It constitutes a nice continuation of the outdoor “radical playground” project during summer 2024.
Health Tech
Health technology assessment (HTA) is an interesting scientific field. The new digital opportunities allow people to participate in medical and medication trials in their homes or even in bed. Their health data and the administration of medication is also encouraged and sometimes supported through digital devices. The pharma and health industries have many devices ready to go. The differences to the traditional forms of medical trials, however, is an issue as we want to compare the results from both kinds of trials. Participants of trials, might prefer or struggle with these novel kinds of study designs. In any case the results will be impacted in several forms (Study Link). In the best of all worlds for the researcher the effects will cancel out each other, but is rather unlikely. Some participants will reach more positive effects with the use of digital tools, whereas others are challenged and might even abandon during the trial. Monitoring during the study (for example through digital inhalors) is another advantage of such distributed trials. Rather than taking adherence to a trial medication for granted, digital tools allow a more precise monitoring of subgroups as well. Data and effort invested in the trial is preserved through the easier access to person’s information, assuming continuous readiness to stay on in the trial.
Our own smartphones are still underexploited in terms of health monitoring and use in research designs. The possibilities to link data to other external data sources shall further advance the research potentials in many interesting ways. Data protection and data security become even more important with the ever smarter phones and connected devices.
Health data
2025 will be a crucial year for health data across the EU. Germany introduced the electronic patient card, which can store basic information to then access data in the health insurance cloud for medical doctors, hospitals and other related health services. Potentially this is a great step ahead as some tests do not have to be repeated if they had been completed recently before already.
In pseudomised form, research may draw samples from such databases to enhance our science based understanding of disease. The evaluation of public health interventions becomes easier and medium and long term efficiency of measures can be assessed in many instances.
The Belgian research using health data has met to discuss the potential and limitations to link health data to other data sources to allow more complete and more complex analyses of health and disease processes. Another extensive data source sits on our smartphone. Collection of steps walked, sleep patterns or heart beats give valuable insights into a person’s own contribution and care about personal health. Although data are frequently incomplete, researchers are used to estimate missing data on the basis of existing or comparable person’s data. The basis for improving health for all are quite promising, data handling and linking them will be a challenge to the competence of all stakeholders and everyone involved in better health. It will be stressful before it becomes a routine.
Shorter is better
Contrary to a lot of received previous recommendations, the shorter duration of antibiotics prescription and use (3-5) days is overall better than the prolonged use of durations between 7-14 days (JAMA Link). A so-called narrative review of medical studies (Lee et al.2023) reports more precise results separate for medical indications (pneumonia, sinusitis etc.), which tend to go in the same direction for the majority of indications. In view of the serious issue of antimicrobial resistance, a consequence of overconsumption and too widespread use of antibiotics (also in animal health and food production), the slogan of shorter is better should receive serious attention.
It is not only a medical, pharmaceutical or public health issue. The topic has become an issue of nutrition as well. The food chain contains largely unknown amounts of antibiotics as well, especially if larger amounts of animal or fish products are part of it.
The knowledge from these sciences has still to filter through to the broader public. This means it has become a social science topic as well. The transmission of knowledge and patient expectations on prescriptions, which is also linked to regulations concerning sick leave, make it more difficult to shorten prescriptions of antibiotics. There is a steep challenge to change behaviour according to the new mantra “shorter is better” with respect to antibiotics, even if we know that it is better for all of us in the medium or long term.
(Image: Jan Harmensz. Muller, De keuze van de rechte levensweg 1571-1628, MRBAB, Brussels)
On Resilience
There are at least 2 definitions of resilience: (1) a material definition points at the “ability to return to an original form or position after being compressed, extended or curved, and (2) a immaterial or psychological definition. The latter one describes the ability to recover, be happy or successful anew having overcome a bad or challenging experience. The American psychological literature defines resilience in the shortest form as “positive adaptation despite adversity”. The psychological construct is linked to a positive life span perspective of personal development. Other areas of application range from “resilient investments”, “resilient industries” to single resilient societies or intergovernmental organizations like the European Union or NATO.
The challenges to resilience increase with complexity of societies and social as well as technical systems. As supply chains have become longer in time and travelling longer distances as well, the improvement of resilience has become a steep challenge for globalization. Reorganizing supply chains with “own sourcing” as in countries which are cut-off from international trade will have huge consequences on sending and receiving countries.
Last, but not least, countries like Ukraine demonstrate the fact and virtue of resilience after more than 1000 days of the massive Russian invasion of its country, which threatened its survival. Resilience works best in networks of organizations and countries. Solidarity is a fundamental building block of resilience as well. Donations and funds support activities that foster resilience.
On Dosage
- Dosage is key. We all know it from everyday expériences. Certainly from drinking alcohol we know the tricks that dosage can have on us. Consumption in small doses is fine and enjoyable, but larger amounts cause all sorts of trouble. In pharmacology the effect of dosage is applied with particular virtue. Small doses even of a poison can have beneficial effects. More of rhe same might well kill you. The same rationale applies to other fields as well. Physiological training effects depend a lot on the right amount of training and the timings or intervals between training sessions. In managerial, economic or social applications the question is not only about what is the right remedy, but also how much of it. The interest rate decisions of central bankers are mostly concerned with dosage rather than « whatever it takes ». A minimum wage increase is equally about dosage and we all have additional examples.
Even in art, take painting or music, dose and pose, that is the question. It is quite surprising that such an overarching issue has received rather little attention, comparatively or only among specialists in each field.
It appears strange, but it is possible to have only a little bit of war, as opposed to comprehensive conflict. The applications of dosage are manifold.
Learning about dosage might prevent binge learning at first and binge viewing later on. In the age of tiktok and social media, dosage has become a key competence. (Image Extract of Gustave Courbet Die Welle 1870, Alte Nationalgalerie Berlin).
On Intersectionality
Society deals with individualization or individualism in various forms. One way is to take each social group as a specific singular case. This is reasonable and justified in many instances. There are cases where this form of dealing with specific social groups comes to limits. Following the rationale of plurality and individualism it has become common practice to address each target group in a specific manner. Intersectionality, however, acknowledges the overlapping of target groups, which necessitates a more specialized approach to intersecting (social) phenomena. Gender might not be the single most important factor to describe a person, just as age is a concept of various intersections. Chronological age versus age defined through biomarkers demonstrate the variety and potential for intersectionality. The Paralympics 2024 in Paris gave another positive example of intersectionality as extraordinary persons achieved previously unimaginable world records in specicialized disciplines. Individualization and classification is only a first step in the scientific endeavour, the analysis of intersectionality is an additional step to consider in a broad range of fields beyond the social sciences.
(Image: Exposition Isa Genzken 75/75 in Neue Nationalgalerie 2023)
Bi-directional Sleep
For most of us bi-directional sleep is a question of sleeping on the left or right side, or on our back or front, head left or right. In immunology bi-directionality of sleep has another meaning. The immune system is linked to sleep in a bi-directional manner. Good sleep enhances the immune response of cells (direction 1) and infected blood cells for example send a signal to the brain to extend sleep. The study by Huynh et al. (2024) in Nature has demonstrated this bi-directional mechanism. It allowed mice who slept well after an imposed heart attack to recover in a better way than those whose sleep got interrupted during the experiment. The most natural response to a heart attack or acute coronary syndrome is more sleep. This is induced by an inflammatory reaction in the brain, which « orders » your body to increase deep sleep. 😴 Sleep is more than just rest, it may be part of healing. ❤️🩹 (people looking at Caspar David Friedrich „Infinite Landscapes“, exhibition Alte Nationalgalerie Berlin 2024)

Water Quality
Obviously, water is not just an issue of quantity, but also quality. The availability of sufficient quantities of water in a region depends on rain, its storage, and the use of these water resources. The quality of water is a subsidiary issue, as lack of inflow causes concentrations of nuisance in water to rise. Global warming will most likely intensity the concern for not only the quantity, but also the quality of water.
Public services are in charge to sample and monitor levels of water quality for consumers. Independent of public, private or public private partnerships in this field there is a need to check from time to time the quality of water. Public institutions do a great job in monitoring water quality, but as science progresses there are new sources of pollution that enter the already complex analysis of water quality. New chemicals and remains of medical or pharmaceutical analyses have been retrieved from water and, sometimes, they have reached critical or unhealthy levels.
More detailed monitoring is necessary and new digital tools allow to improve just this type of monitoring to inform policy makers on shifting patterns.
A project of that type “Urban Green Eye”, for example, allows to monitor the artificialization of previous vegetation to show up on satellite images of Germany. Independent groups, citizens or communities might find it useful to use their own sampling and testing to guard against abuses or dysfunctional public monitoring systems. Start-ups like “Hydroguard” offer services to support activists, communities or public services in their own efforts to ensure water quality.
Public health info
Public services have a premordial role to play in providing reliable and up-to-date information on health issues. It is no longer only in charge of collecting this information, for example on infectious diseases, but public services are in charge of timely disemination of that info as well. This is, of course, were online services and AI come into play. Getting out this info is crucial, but in the age of fake news and the wide disemination of news on social media, public services need to check also what becomes of the news they have published. The Covid-19 pandemic has been a worthwhile experience in this respect. It is important that reliable information is transmitted via trustworthy channels, which have already been established prior to the “next” health crisis. Many innovative tools were presented at the SCCON 2024 and maybe trustworthy video calls with a medical doctor or your pharmacist may constitute a solution to many infectious pandemics. However, trust in the technology is important as well as equipment and identification systems to be sure that your medical doctor you meet online is actually a medical doctor or only a savy pretender. The issue is as old as medical assistance. The RKI in Germany is the reference information for coordinated information on many public health issues like infectious diseases.
(Image: Extract of David Ryckart d.J. 1612-61, Der Dorfchirurg, SPK Gemäldegalerie Berlin)
Risk Takers
We are all risk takers of one form or the another. Those of us who ride motorbikes or enjoy rock climbing have an above average taste for risk taking. Since the publication of „The risk society“ we are aware that collectively as a society we have taken on additional risks like nuclear energy, atomic weapons or the risk associated with silent climate change with the persistent reliance on fossil fuels to a large extent. Holman W. Jenkins (WSJ) has added an additional perspective on risk takers which originates from government policies to encourage building homes in places subject to high risks of flooding. Several policies come to mind that encourage individuals to take high risks and construct and repair buildings in flood prone areas. Government grants, insurance policies and relocation subsidies are at issue here. Regulations like driving licenses try to build on competences to ensure „more rational risk taking“ in people. Teaching about nutrition might alleviate the obesity pandemic as much as awareness of an active lifestyle can avoid a large number of cardiovascular diseases. Risk taking should be to a large extent an individual’s choice with the consequence to live up to the consequences of the risks taken also more an individual’s responsibility. Collective solutions are a powerful way to encourage additional risk taking. The consequences of those well-defined solutions have to be funded collectively as well. A society-wide discussion and voting process on such issues has to be organized and updated from time to time. (Image Skateboard high and long jumps Brussels 2024-10)

Science Fraud
It is a big issue if publications in science in high reputation journals have managed to pass a rather lengthy and thorough peer review process and still contain evidence based on fraudulent data. The worst case scenario that based on this wrong evidence tests of useless drugs are performed on patients in hope of an honest concern for their health. In fact the financial rewards and even academic rewards have been achieved only through the successful publication of a bias introduced into the data and/or analyses of the data. The fraudulent researcher became subsequently Director of the institute of agingwhoch is part of the American National Institute of Health (NIH) and an academic reference in health sciences far beyond the USA. It is the merit of Charles Piller and his team to persist in challenging the treatment recommendations which were concerning Alzheimer and Parkinson diseases. The checks and balances in the academic research have failed and a serious reconsideration of the procedures should follow, not just business as usual. The reputation of scientific research is at stake beyond the natural sciences and medicine, although the normal way of proceeding is just to qualify such events as singularity and specific to a single discipline. Aging is also not just treated by one single discipline. Hence, there is a need to review the review process and publication practices. The Boeing airplane control failures were also indicating that reviews of technology are subject to high risks. Independent checks and control are hard to ensure in advanced subject matters, but sufficient time and resources have to be devoted to the process. (Image Repair Lab Deutsches Technikmuseum DTM2024).

Happy Runner
The happy runner is a nice example of how hard it maybe to experience happiness through running. The so-called runner’s high is available to everybody, if you manage to run long enough already. Most predictions put the threshold distance at about a 1 hour run. The reward for this effort is a special feeling that exceeds the pain or it makes you forget or supress the pain at least temporarily. Special reinforcements can be achieved through the big city runs in exciting places with thousands of people cheering you on. This has become a big business as well. Training for such an event might raise your feeling of happiness substantially. The chemistry of the endogenous production of stimulants of happiness in our body has been enlightened substantially in recent years (partly as doping control). Most of the brain active drugs our body can produce itself, although this involves a lot of physical and mental effort. The rewards are pretty healthy for most runners contributing to their basic level of happiness. Running outside, has contributed more to happiness for me more than the same exercise on a treadmil. Maybe, the environment is part of the happy runner’s high effect.
Happy Biology
At first glance happiness from a biological perspective is easy to understand. Its hormones, stupid, that regulates it all. Only problem, there are many of them that interact and, apparently, a lot depends on the right dosis and duration of exposure or deficiency. Oxytocin deficiency seems to be a corollary of anxiety and lack of pro-social behavior, potentially making people less happy – to put it bluntly. There are other complex interactions between hormones not only in the circadian circle of humans like for cortisol, but also related to differential reactions to stress. Genetics and epigenetics are involved as well stress regulation and early exposition to stress during the life course has longer lasting consequences later on. How much stress is good for you? Climbing Mountains induces physical stress, but most people report lasting happiness referring back to such singular events. Hormones seem to play tricks with us as well.
Some time after the novel “Klara and the Sun“, endocrinologists have documented the positive effect of a robot on oxytocin levels in humans. Improvements to mental health and well-being are apparently easy considering that oxytocin is a driver of feeling happy as well. Maybe we should take our depressors and drivers of oxytocin more seriously to be “biologically” happy.
(Image: Extrait Frans Hals 1660, Catharina Hooft and her nurse. Exhibition Gemäldegalerie Berlin 2024)
Happy Employee
The research on happiness, subjective well-being or overall satisfaction with your life is also an empirical question. Analyses of being happy donot only focus of overall happiness, but look much more into the details of happiness. Beyond the tricky longitudinal observations of happiness it is common scientific practice to deal with subdomains of happiness like satisfaction of employees with their job, satisfaction with one’s job beyond the honeymoon and hangover effect, best known from family studies.
Each of those subdomains has a significant effect on overall happiness. The novel “Happy Life” by David Foenkinos is an interesting example which focuses mainly on the subdomains of job satisfaction, satisfaction with private and romantic partners as the major domains of a happy life. As developed in the novel, people make job changes to re-orientate professional careers or reset their private life. A low point on the happiness scale in one domain might be compensated by higher levels in another domain. These impact from one domaine to another might have substantial time lags involved as well. More drastic resets (à la Foenkinos) can be avoided through focus on other subdomains of overall happiness as well.
How happy are you with your housing situation, neighborhood, your pet, your physical health? There a multiple +/-spill-over effects to overall happiness. Reading a novel might be one as well, just take time reserved to yourself.(Image BnF expo “women in sport”, 20024)